![]() The chance of having this occur is very low. In most of these people, symptoms began within 42 days (6 weeks) after receiving the Janssen (Johnson and Johnson) COVID-19 vaccine. Guillain-Barré syndrome (a nervous system disorder in which the body's immune system damages nerve cells, causing muscle weakness and sometimes paralysis) has occurred in some people who have received the Janssen (Johnson and Johnson) COVID-19 vaccine. Signs of a severe allergic reaction can include: ![]() A severe allergic reaction would usually occur within a few minutes to one hour after getting a dose of the Janssen (Johnson and Johnson) COVID-19 vaccine. ![]() There is a remote chance that the Janssen (Johnson and Johnson) COVID-19 vaccine could cause a severe allergic reaction.
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